Trajectory of laboratory and clinical metabolic risk factors in people with prediabetes prior to diabetes development

N. Ahmadi, M. Valizadeh ,D. Khalili ,F. Hadaegh ,N. Saadat ,M. Mahdavi

Research institute for endocrine sciences, Shahid Beheshti University of Medical Sciences , Tehran, Iran

INTRODUCTION

• prediabetes is dysglycemic state with high rate of progression to diabetes. conversion rate from prediabetes to diabetes is about 5-10% annually in different population.
• Although the lifetime risk to progress from prediabetes to diabetes is high (74%) , but progression of prediabetes to diabetes is preventable with lifestyle changes or pharmacological interventions.
• It is important to know the risk factors of progression and the trajectory of these risk factors in prediabetic individuals.
• It can help the clinicians to start preventive intervention in accurate time when these risk factors deteriorate before diabetes occurrence.